FRI-760 Natural Agents Against Candida in Human Digestive System

Friday, October 12, 2012: 11:00 PM
Hall 4E/F (WSCC)
Liz Y. Lugo-Cordero, BS , Biology, University of Puerto Rico, Mayaguez Campus, Mayaguez, PR
Maria M. Vargas-Rodriguez, PhD , Biology, University of Puerto Rico, Mayaguez Campus, Mayaguez, PR
Candida albicans is part of the human microflora; however, it is also an opportunistic pathogen in high concentrations causing infections.  This yeast lives in a simbiotic relationship with humans in the mucosal regions of the digestive system; nevertheless, it has been linked to overweight. When concentration of C. albicans increase, bacteria can't keep balance in our digestive system and people find it difficult to weight loss.  This research consists in studying the effects of natural agents against C. albicans in human digestive system. Natural products, “Yeast-Cleanse"© and "Candida Plus"©, were used with inhibition disks at concentrations of: 25%, 50%, 75% and 100%.  To compare the effect of the yeast at different conditions similar to the acidic pH of the stomach, plates containing Saboureaud Dextrose Agar (SDA) and a C. albicans striated, at pH 3.98, 4.57 and 5.2, were inoculated with the discs and incubated.  Inhibition halos were compared for each treatment.  Results indicate that "Candida Plus"© was not successful against Candida, since no inhibition was detected. In contrast, “Yeast-Cleanse"© showed an area of inhibition in all tests performed, reflecting that this product is more efficient.  Results provide “Yeast-Cleanse"© as a possible alternative to treat excess of C. albicans in human digestive system, and further on helping people to their weight loss.  We expect that some of the active ingredients of these products will show inhibition halos through a new experimentation.  Further research on effects of C. albicans on the metabolism will provide more understanding of how this yeast affects weight.