SAT-855 Transvection at the eyes absent Gene of Drosophila in the Presence of Various zeste Alleles

Saturday, October 13, 2012: 12:20 AM
Hall 4E/F (WSCC)
Nagma Shah , Biology, Brandeis University, Waltham, MA
James Morris, MD, PhD , Biology, Brandeis University, Waltham, MA
The eyes absent (eya) gene in Drosophila is necessary for the endurance and differentiation of eye stem cells. Losing this gene function causes the adult compound eye to become reduced or not present; however specific combinations of various eya alleles demonstrate partial complementation where the eyes can return to full size. This partial complementation is dependent on the location of the two alleles in the genome. Interaction at the eya gene also requires normal zeste function. Various zeste alleles, that may or may not all have the same effect on transvection, will be tested with various eya alleles. If the product of these genes affect transvection, it can be helpful in better understanding the structure and dynamics of chromosomes.